Skullcap (Scutellaria lateriflora)

Body Focus: Nervous System
Constituents: Baicalin, scutellarin, wogonin, flavones
Cellular Mechanism: These flavones bind to GABA_A receptor sites, enhancing inhibitory neurotransmission to reduce neural excitability. Baicalin also modulates microglial inflammation, which may help protect neurons from oxidative stress.
Traditional & Modern Use: Revered in Western herbalism as a “nerve tonic,” skullcap calms racing thoughts, supports rest, and eases anxious tension.
Formulations: Glycerites, tinctures, or teas for daily stress modulation.
Pair Well With: Blue lotus for tranquility, reishi for adaptogenic balance, or lemon balm for mood uplift.